Endocrine Abstracts

Current trust protocol for the Short Synacthen Test (SST) is to perform cortisol levels at 0, 30 min and 60 min; there is a variation in this policy in different trusts. This quality improvement project determined if the 60 min test was significant and, if so, in what proportion of patients. A further aspect of the audit was in regards to determining if the number of SSTs in the trust could be reduced. We investigated every adult having a SST run through the SWFT laboratory du...

We present the case of a young man who had been known to the endocrine department with difficult to control hyperthyroidism and atrial fibrillation. After a period of treatment with carbimazole, during which he missed several appointments, he was referred for radioactive iodine therapy, which was administered in January 2013. He failed to attend for follow-up appointments and continued to take carbimazole.He was subsequently referred to the acute medicin...

Hypocalcaemia is a common presentation to the emergency department; patient’s symptoms vary but typically report pins and needles and muscle cramps, due to neuromuscular irritability. Other important features include ECG changes (prolonged QTc) and seizures. The most common causes are hypoparathyroidism, vitamin D deficiency and chronic kidney disease.A 25-year old male presented with symptomatic hypocalcaemia who was referred to us for follow up, a...

We present a 71-year-old gentleman who was referred with a 3-month history of tiredness and proximal myopathy, diarrhoea, rapid weight loss and new onset diabetes mellitus.On examination, he had features consistent with cortisol excess including thin skin, abdominal striae, proximal muscle wasting and peripheral oedema to his thighs. Neck examination revealed a palpable 2-cm right-sided thyroid nodule.Laboratory investigations show...

We have previously demonstrated that 80% of patients with PTHP will have co-existing vitamin D deficiency suggesting an increased metabolism of vitamin D. There are few data assessing the impact and safety of different vitamin D preparations on calcium, parathyroid hormone (PTH) and vitamin D in this group. Here, we report the details of replacement therapy using different vitamin D preparations. In a retrospective study of 22 (20F:2M and 8 Asian:14 Non-Asian) patients with co...